Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10837923 | Pharmacology Biochemistry and Behavior | 2013 | 9 Pages |
Abstract
⺠Convolutamydine A and two analogues were evaluated in nociceptive models. ⺠Substances demonstrated peripheral antinociceptive effects. ⺠A supraspinal analgesic effect was observed in the hot plate model. ⺠The effects of convolutamydine A are mediated by all three systems. ⺠Analogues action involves the cholinergic and nitric oxide systems.
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Authors
Gabriela S.M. Figueiredo, Renata S. Zardo, Bárbara V. Silva, Flávio A. Violante, Angelo C. Pinto, Patricia D. Fernandes,