Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10837938 | Pharmacology Biochemistry and Behavior | 2013 | 6 Pages |
Abstract
⺠Sickness behavior is a motivational state triggered by activation of immune system. ⺠Both a detrimental and beneficial role of NO was observed during immune challenges. ⺠The inhibition of iNOS accentuate LPS-induced the behavioral changes. ⺠NO may have a protective role to limit LPS-induced sickness behavior.
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Authors
Deidiane E. Ribeiro, Viviane M. Maiolini, Roseli Soncini, José Antunes-Rodrigues, Lucila L.K. Elias, Fabiana C. Vilela, Alexandre Giusti-Paiva,