Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10837940 | Pharmacology Biochemistry and Behavior | 2013 | 11 Pages |
Abstract
⺠Involvement of imidazoline receptors in oxycodone antinociception was determined. ⺠Efaroxan (EFX) and BU224 were used to determine involvement of I1 and I2 receptors. ⺠Oxycodone antinociception was unaffected by efaroxan but was blocked by BU224. ⺠BU224 but not EFX blocked agmatine/BMS182874-potentiated oxycodone antinociception. ⺠Imidazoline I2 but not I1 receptors are involved in oxycodone antinociception.
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Authors
Shaifali Bhalla, Izna Ali, Hyaera Lee, Shridhar V. Andurkar, Anil Gulati,