| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10837963 | Pharmacology Biochemistry and Behavior | 2011 | 7 Pages |
Abstract
⺠MDMA-induce CPP can be reinstate after extinction by a priming dose. ⺠The role of the cannabinoid system on the reinforcing effects of MDMA is not clear. ⺠No study has evaluated its role on the reinstatement of MDMA drug-seeking behavior. ⺠CB1 agonist WIN55212-2 and CB1 inverse agonist/antagonist SR141716A were used. ⺠The acute blockade of the endocannabinoid system reinstates MDMA-induced CPP. ⺠WIN 55212-2 increases the effect of a non-effective priming dose of MDMA.
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Authors
M. Daza-Losada, J. Miñarro, M.A. Aguilar, O. Valverde, M. RodrÃguez-Arias,