Article ID Journal Published Year Pages File Type
10837985 Pharmacology Biochemistry and Behavior 2011 8 Pages PDF
Abstract
► Withdrawal from a single dose of PCP alters behavior in animal models of anxiety. ► Effects are age, sex and task dependent. ► In adults, PCP is anxiogeneic in males and anxiolytic in females in EPM and light dark test. ► In young adults, PCP is anxiogenic in the EPM and anxiolytic in the light dark test.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
The effects of phencyclidine (PCP) on anxiety-like behavior in the elevated plus maze and the light-dark exploration test are age dependent, sexually dimorphic, and task dependent
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