| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10837990 | Pharmacology Biochemistry and Behavior | 2012 | 11 Pages |
Abstract
⺠MSX-4 is a novel adenosine A2A antagonist prodrug, converted into MSX-2 in vivo. ⺠MSX-4 reversed the effects of eticlopride on effort-related choice behavior. ⺠MSX-4 increased locomotion in eticlopride-treated rats. ⺠MSX-4 suppressed galantamine-induced tremulous jaw movements in rats. ⺠MSX-4 may be useful for treating parkinsonism and depression.
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Authors
Jessica L. Santerre, Eric J. Nunes, Rotem Kovner, Chelsea E. Leser, Patrick A. Randall, Lyndsey E. Collins-Praino, Laura Lopez Cruz, Merce Correa, Younis Baqi, Christa E. Müller, John D. Salamone,