Article ID Journal Published Year Pages File Type
10838008 Pharmacology Biochemistry and Behavior 2012 6 Pages PDF
Abstract
► Morphine induces differential CTAs in F344 and LEW rats (F > L). ► Morphine's differential effects may be mediated centrally or peripherally. ► The peripheral mu agonist loperamide induced similar aversions in the two strains. ► Differences in loperamide and morphine's effects in F344/LEW rats were discussed.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Assessment of the aversive effects of peripheral mu opioid receptor agonism in Fischer 344 and Lewis rats
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