Article ID Journal Published Year Pages File Type
10838015 Pharmacology Biochemistry and Behavior 2012 8 Pages PDF
Abstract
► Assessed whether social isolation (SI) & MK-801 would create a robust animal model of SZ. ► Assessed locomotor activity, GAT-1 & GABAA receptors in the frontal cortex and hipp. ► SI increased activity, GAT-1 & GABAA receptor activity in the frontal cortex. ► MK-801 increased GABAA receptor activity in the hippocampus. ► SI & MK-801 may act through different mechanisms.
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