Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10838015 | Pharmacology Biochemistry and Behavior | 2012 | 8 Pages |
Abstract
⺠Assessed whether social isolation (SI) & MK-801 would create a robust animal model of SZ. ⺠Assessed locomotor activity, GAT-1 & GABAA receptors in the frontal cortex and hipp. ⺠SI increased activity, GAT-1 & GABAA receptor activity in the frontal cortex. ⺠MK-801 increased GABAA receptor activity in the hippocampus. ⺠SI & MK-801 may act through different mechanisms.
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Authors
Andrea J. Hickey, James N. Reynolds, Richard J. Beninger,