| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10838086 | Pharmacology Biochemistry and Behavior | 2011 | 10 Pages |
Abstract
⺠The role of central noradrenergic neurons in depression was reexamined in mice. ⺠Lesions with ivt DSP4 or DBH-SAP reduced depression and increased motor activity. ⺠Lesion effects were greatest with partial LC destruction plus damage to 5HT system. ⺠Results support a depressant behavioral role for brainstem monoaminergic neurons.
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Authors
Yan Lin, Yasmeen Sarfraz, Ashley Jensen, Adrian J. Dunn, Eric A. Stone,