Article ID Journal Published Year Pages File Type
10838108 Pharmacology Biochemistry and Behavior 2012 8 Pages PDF
Abstract
► SYA013 inhibits d-amphetamine-induced locomotor hyperactivity in rats. ► SYA013 inhibits CAR in a dose dependent manner without escape failure responses. ► SYA013 has a log BB of 1.48 suggesting it readily crosses the BBB. ► WAY100,635 did not have a significant effect on the lack of catalepsy. ► 5HT1A receptor does not contribute significantly to the pharmacological profile.
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