Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10838113 | Pharmacology Biochemistry and Behavior | 2012 | 9 Pages |
Abstract
⺠Effect of the cannabinoid WIN 55,212-2 (WIN) in rat models of type 1 and 2 diabetes. ⺠WIN alleviates mechanical allodynia in both models of type 1 and 2 diabetes. ⺠In type 1 diabetes, WIN effect is mediated by CB1 and CB2 receptors. ⺠In type 2 diabetes, CB2 receptors might not be involved. ⺠At the doses used, WIN does not exert any psychoactive effect.
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Authors
Gema Vera, Visitación López-Miranda, Esperanza Herradón, MarÃa Isabel MartÃn, Raquel Abalo,