Article ID Journal Published Year Pages File Type
10838124 Pharmacology Biochemistry and Behavior 2011 5 Pages PDF
Abstract
► Combinations of analgesics are commonly used in the management of chronic pain. ► Synergistic effects of nociceptin/orphanin FQ and cannabinoid systems are examined. ► Both JTC-801 and WIN 55,212-2 produced dose-dependent anti-allodynic effects. ► Co-administration of these drugs resulted in a synergistic interaction. ► This combination may have utility in neuropathic pain pharmacotherapy.
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