Article ID Journal Published Year Pages File Type
10838134 Pharmacology Biochemistry and Behavior 2011 5 Pages PDF
Abstract
► 6-OHDA induces motor changes in male rats when injected in corpus striatum. ► Parkinsonism in rats is expressed by motor changes induced by apomorphine. ► Hemiparkinsonism in rats also induces cognitive and affective changes. ► Progesterone is able of preventing the onset of cognitive and affective changes. ► Imipramine is able of reverting the depression-like behavior of rats.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Progesterone prevents depression-like behavior in a model of Parkinson's disease induced by 6-hydroxydopamine in male rats
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