Article ID Journal Published Year Pages File Type
10838162 Pharmacology Biochemistry and Behavior 2011 4 Pages PDF
Abstract
► Illicit abuse of analgesics containing hydrocodone and acetaminophen is on the rise. ► Hydrocodone produced CPP in rats, whereas acetaminophen was devoid of such effect. ► When combined, acetaminophen enhanced hydrocodone CPP in a dose specific manner. ► Hydrocodone caused locomotor activity. ► When combined, acetaminophen did not enhance hydrocodone-induced locomotion.
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