Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10838162 | Pharmacology Biochemistry and Behavior | 2011 | 4 Pages |
Abstract
⺠Illicit abuse of analgesics containing hydrocodone and acetaminophen is on the rise. ⺠Hydrocodone produced CPP in rats, whereas acetaminophen was devoid of such effect. ⺠When combined, acetaminophen enhanced hydrocodone CPP in a dose specific manner. ⺠Hydrocodone caused locomotor activity. ⺠When combined, acetaminophen did not enhance hydrocodone-induced locomotion.
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Authors
Arbi Nazarian, Deepthi Are, John M. Tenayuca,