| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10838163 | Pharmacology Biochemistry and Behavior | 2011 | 5 Pages |
Abstract
⺠5-Methoxy-N,N-dimethyltryptamine is a naturally-occurring hallucinogen. ⺠CYP2D6-humanized mice have increased levels of bufotenine following 5-MeO-DMT. ⺠Wild type and Tg-CYP2D6 mice did not differ in rate of acquisition of stimulus control. ⺠5-MeO-DMT did not generalize to bufotenine and only partially to acetylbufotenine. ⺠Harmaline, a mono amine oxidase inhibitor, enhanced the stimulus effects of 5-MeO-DMT.
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Authors
J.C. Winter, D.J. Amorosi, Kenner C. Rice, Kejun Cheng, Ai-Ming Yu,