Article ID Journal Published Year Pages File Type
10838167 Pharmacology Biochemistry and Behavior 2011 7 Pages PDF
Abstract
► CA exhibited considerable antidepressant activity by showing decrease in immobility period in the Porsolt's swim stress-induced behavioral despair test and escape failures in Learned “helplessness test”. ► The antidepressant activity was further confirmed by its modulating effect on nor-adrenaline (NA), dopamine (DA) and 5- hydroxy tryptamine (5-HT). ► A regulating effect on lipid per oxidation, glutathione (GSH) and glycogen in liver of chronically stressed mice was also shown. ► It also normalized the raised corticosterone levels, the main marker of stress response in rodents.
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