| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10838181 | Pharmacology Biochemistry and Behavior | 2011 | 7 Pages |
Abstract
⺠Buspirone coadministration at the dose of 1.0 mg/kg could attenuate apomorphine-induced motor sensitization. ⺠An increase in the inhibitory serotonergic influence on dopaminergic neurons may be the mechanisms by which buspirone could attenuate apomorphine-induced motor sensitization. ⺠Increase in the sensitivity of somatodendritic 5-HT1A receptors may have an important role in apomorphine-induced sensitization. ⺠Findings may have important consequences in the use of apomorphine for the treatment of Parkinson's disease.
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Authors
Huma Ikram, Darakhshan Jabeen Haleem,