| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10838192 | Pharmacology Biochemistry and Behavior | 2011 | 6 Pages |
Abstract
⺠Diclofenac and indomethacin produce antinociception in the rat formalin test. ⺠Sulfonylureas and biguanides block the diclofenac-induced antinociception. âºSulfonylureas and biguanides do not block the indomethacin-induced antinociception. ⺠Diclofenac, but not indomethacin, produces antinociception activating K+ channels. ⺠Diclofenac produces antinociception activating biguanides-induced mechanisms. ⺠Indomethacin does not activate biguanides-induced mechanisms.
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Authors
Mario I. Ortiz,