Article ID Journal Published Year Pages File Type
10838206 Pharmacology Biochemistry and Behavior 2011 4 Pages PDF
Abstract
► Beta lactam antibiotics offer neuroprotection by increasing GLT-1 expression. ► Ceftriaxone prevents the development of tolerance and dependence to opioids. ► Cannabinoid tolerance is known to be similar to opioids. ► Ceftriaxone attenuated the development of tolerance to the cannabinoid. ► GLT-1 transporter inhibitor reversed the preventive effect of ceftriaxone.
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