Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10838206 | Pharmacology Biochemistry and Behavior | 2011 | 4 Pages |
Abstract
⺠Beta lactam antibiotics offer neuroprotection by increasing GLT-1 expression. ⺠Ceftriaxone prevents the development of tolerance and dependence to opioids. ⺠Cannabinoid tolerance is known to be similar to opioids. ⺠Ceftriaxone attenuated the development of tolerance to the cannabinoid. ⺠GLT-1 transporter inhibitor reversed the preventive effect of ceftriaxone.
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Authors
Ozgur Gunduz, Cagatay Oltulu, Ahmet Ulugol,