| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10838232 | Pharmacology Biochemistry and Behavior | 2011 | 8 Pages |
Abstract
⺠Peripheral KYN/TRP ratio is related to stress-related behaviors in UCMS mice. ⺠Peripheral KYN/TRP ratio is related to high 5-HT metabolism in prefrontal cortex. ⺠Peripheral KYN/TRP ratio is negatively correlated with KYNA levels in amygdala.
Keywords
QUINIDO5-HIAATDOTrpUCMS3-hydroxykynurenine5-Hydroxyindoleacetic acidAmygdalahippoUnpredictable chronic mild stresskynurenic acidQuinolinic acidAnxietyDepressionAMYinterferonIFNindoleamine-2,3-dioxygenaseTryptophantryptophan-2,3-dioxygenaseKYNAnimal modelkynurenine pathwayMiceHippocampushigh performance liquid chromatographyHPLCcingulate cortexKYNAkynurenine
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Authors
Anthony Laugeray, Jean-Marie Launay, Jacques Callebert, Alexandre Surget, Catherine Belzung, Pascal R. Barone,