Article ID Journal Published Year Pages File Type
10838276 Pharmacology Biochemistry and Behavior 2011 5 Pages PDF
Abstract
► Long-term methadone treatment impairs cognitive functioning in rats. ► The impairment is not dependent on presence of methadone in brain tissue. ► Long-term methadone treatment did not increase the drug metabolism. ► Experimental animal studies are important in a field with severe knowledge gaps.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Long-term methadone treatment impairs novelty preference in rats both when present and absent in brain tissue
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