Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10838314 | Pharmacology Biochemistry and Behavior | 2011 | 7 Pages |
Abstract
⺠Blocking endogenous cannabinoid signaling at CB1 receptors reduces weight gain. ⺠AM4113 induces a transient inhibition of food intake. ⺠Inhibition of weight gain is due to reduced food intake not changes in metabolism. ⺠Chronic AM4113 treatment alters neither brain nor plasma 2-AG levels.
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Authors
Nina L. Cluny, Adam P. Chambers, V. Kiran Vemuri, JodiAnne T. Wood, Lindsay K. Eller, Carmelina Freni, Raylene A. Reimer, Alexandros Makriyannis, Keith A. Sharkey,