Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10838440 | Pharmacology Biochemistry and Behavior | 2005 | 6 Pages |
Abstract
Ten and 100 Hz EA significantly inhibited CFA-induced hind paw hyperalgesia. Both 10 and 100 Hz EA combined with the sub-effective dose of 0.001 mg/rat MK-801 showed prolonged anti-hyperalgesia with no side effects. These results demonstrate that EA combined with a sub-effective dose of this NMDA receptor antagonist enhances anti-hyperalgesia, and this combination may provide an effective strategy for pain management.
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Authors
Rui-Xin Zhang, Linbo Wang, Xiaoya Wang, Ke Ren, Brian M. Berman, Lixing Lao,