| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10838839 | Pharmacology Biochemistry and Behavior | 2005 | 6 Pages |
Abstract
The present data demonstrated an enhancement of the antidepressant-like effect by joint administration of IMI and magnesium in the FST, and further indicate the particular role of magnesium in the antidepressant action. Since there was no increase in IMI, DMI or magnesium concentration after joint administration of magnesium and IMI, the data suggest that pharmacodynamic rather than pharmacokinetic interaction between magnesium and IMI is accountable for behavioral effect in the FST.
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Authors
Ewa Poleszak, Piotr Wlaź, Bernadeta Szewczyk, Ewa KÄdzierska, Elżbieta Wyska, Tadeusz Librowski, Joanna Szymura-Oleksiak, Sylwia Fidecka, Andrzej Pilc, Gabriel Nowak,