Article ID Journal Published Year Pages File Type
10838854 Pharmacology Biochemistry and Behavior 2005 12 Pages PDF
Abstract
These results strongly suggest that activation of 5-HT2A receptors is critically involved in the anxiolytic activity of milnacipran. On the other hand the lack of activity of milnacipran after depletion of NA or 5-HT is consistent with milnacipran acting on the locus coeruleus to induce 5-HT release. The present data suggest a strong connection between 5-HT2A receptors and NA neurotransmission.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Anxiolytic-like effect of milnacipran in the four-plate test in mice: Mechanism of action
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