Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10843307 | Protein Expression and Purification | 2012 | 7 Pages |
Abstract
⺠A novel hybrid protein combining LL-37 with haFGF was designed for the first time. ⺠LL-37-haFGF with antibacterial activity was successfully expressed in Escherichia coli and purified. ⺠LL-37-haFGF was shown to be able to stimulate NIH 3T3 cells proliferation as haFGF. ⺠LL-37-haFGF displayed even improved antimicrobial activities compared with LL-37. ⺠The recombinant LL-37-haFGF may have important potential application in wound healing.
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Authors
Juan Shen, Xue-mei Lu, Xiao-bao Jin, Jing Ding, Xiao-bo Li, Han-fang Mei, Fu-jiang Chu, Jia-yong Zhu,