| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10845292 | Regulatory Peptides | 2011 | 9 Pages |
Abstract
⺠Decanoyl ghrelin (D-Ghr) is a ghrelin peptide modified with a n-decanoic acid. ⺠A considerable amount of D-Ghr was detected in human plasma by our D-Ghr RIA. ⺠Plasma D-Ghr exhibited a different kinetics from that of octanoyl ghrelin after meal. ⺠The ratio of plasma D-Ghr to total ghrelin was high in the subject with higher BMI. ⺠These dynamics of D-Ghr might account for the deregulation of appetite in obesity.
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Authors
Junko Yoh, Yoshihiro Nishi, Hiroshi Hosoda, Yuji Tajiri, Kentaro Yamada, Toshihiko Yanase, Ryosuke Doi, Koji Yonemoto, Kenji Kangawa, Masayasu Kojima, Eiichiro Tanaka, Jingo Kusukawa,