Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10845342 | Regulatory Peptides | 2005 | 6 Pages |
Abstract
The present results confirm our previous data showing that ghrelin inhibits insulin and stimulates glucagon secretion from pancreatic islets of the mouse and we now show similar effects in rat islets. The effects of ghrelin were accompanied by an increased rate of NO production. Conceivably, ncNOS activation partly accounts for to the inhibitory effect of ghrelin on insulin secretion and the stimulatory effect of ghrelin on glucagon secretion.
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Authors
Saleem S. Qader, Ingmar Lundquist, Mats Ekelund, Rolf HÃ¥kanson, Albert Salehi,