Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10845382 | Regulatory Peptides | 2005 | 6 Pages |
Abstract
In conclusion, this study shows that BK upregulates IL-1β- and TNFα-stimulated IL-8 production via BK B2 receptor and that PKC signal pathway seems to be involved in the upregulation of the cytokine-induced IL-8 production in gingival fibroblasts. This stimulatory effect of BK on IL-8 production may contribute to the maintenance of the gingival inflammation and enhanced risk for destruction of gingival connective tissue.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Gustaf Brunius, Helena Domeij, Agneta Gustavsson, Tülay Yucel-Lindberg,