Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10847677 | Steroids | 2015 | 7 Pages |
Abstract
We demonstrated large inter-individual variability in anastrozole and anastrozole metabolite concentrations as well as E1, E2, E1-C, A, and T concentrations before and while on anastrozole. These findings suggest that the standard 1Â mg daily dose of anastrozole is not optimal for a substantial proportion of women with breast cancer.
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Authors
James N. Ingle, Krishna R. Kalari, Aman U. Buzdar, Mark E. Robson, Matthew P. Goetz, Zeruesenay Desta, Poulami Barman, Tanda T. Dudenkov, Donald W. Northfelt, Edith A. Perez, David A. Flockhart, Clark V. Williard, Liewei Wang, Richard M. Weinshilboum,