Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10847807 | Steroids | 2005 | 4 Pages |
Abstract
We describe the synthesis of 3-oxo-4-aza-5α-androst-1-ene-17β-(N-tert-butylcarboxamide) (finasteride) from 4-androstene-3,17-dione (AD) in seven steps in an overall yield of 18.6% via oxidation, ammoniumation, dehydration, and dehydrogenation.
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Authors
Zhong-Xing Jiang, Jing-Quan Ye, Li Jiang, Ying-Sheng Zhao,