| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10847853 | Steroids | 2005 | 13 Pages |
Abstract
Twenty-seven new pregnane glycosides were isolated from the whole plant of Caralluma dalzielii, and their structures elucidated from extensive 2D NMR analysis as well as ESI-MS experiments. All isolated compounds were tested for their antiproliferative activity on J774.A1, HEK-293, and WEHI-164 cell lines. Moderate to high potency of cytotoxicities were found in almost all tested compounds, confirming the significant cytotoxic activity of pregnane glycosides.
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Authors
Marinella De Leo, Nunziatina De Tommasi, Rokia Sanogo, Giuseppina Autore, Stefania Marzocco, Cosimo Pizza, Ivano Morelli, Alessandra Braca,