Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10848025 | Steroids | 2013 | 7 Pages |
Abstract
- 16,22-Diketocholesterol is a novel ligand for oxysterol-binding protein Osh4.
- We have determined X-ray structure of 16,-22-diketocholesterol bound to Osh4.
- Our diketocholesterol-Osh4 structure may represent a structural intermediate between open and closed conformations.
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Authors
Myong Chul Koag, Young Cheun, Yi Kou, Hala Ouzon-Shubeita, Kyungjin Min, Arthur F. Monzingo, Seongmin Lee,