Article ID Journal Published Year Pages File Type
10848079 Steroids 2012 8 Pages PDF
Abstract
► Ciliate DES5A gene restores ergosterol biosynthesis in erg3 Saccharomyces cerevisiae strain. ► DES5A gene reverses the hypersensitivity to cycloheximide in erg3 strain. ► Des5Ap is localized in endoplasmic reticulum of Tetrahymena thermophila and S. cerevisiae.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
The cytochrome b5 dependent C-5(6) sterol desaturase DES5A from the endoplasmic reticulum of Tetrahymena thermophila complements ergosterol biosynthesis mutants in Saccharomyces cerevisiae
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