| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10848115 | Steroids | 2005 | 6 Pages |
Abstract
Treatment of 3β-hydroxyl-5-Πsteroids with anhydrous FeCl3 in CH2Cl2 afforded reasonable yields of the corresponding alkyl chlorides with a retention of configurations. The structures of the chlorine-exchanging products were determined by NMR and HRMS spectra. The absolute configurations were confirmed by X-ray crystal analysis of 3β-chloro-androst-5-en-17-one. The generality and scope of the reaction were also investigated.
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Biochemistry
Authors
Feng-Wu Liu, Hong-Min Liu, Yan-Bing Zhang, Jing-Yu Zhang, Li-Huan Tian,