Le bon usage du médicament dans la prise en charge du patient Alzheimer Perspectives et recommandations

During Alzheimer's disease, the main objectives of care are to improve, stabilize or delay the progression of cognitive deficits and their impact on daily life, and minimize the psychological and behavioral manifestations arising from or associated with them. The treatment relies on a combination of specific therapeutic classes for the management of cognitive and non-cognitive disorders. Naturally involved in the optimal clinical use of drugs involed in Alzeimer's disease and individualized treatments, the clinical pharmacist should be familiar with the different mechanisms of action as well as physical and chemical properties and pharmacokinetics of different molecules, but also define the effective doses taking into account the risk / benefit ratio which is to define the maximum tolerated doses of each individual. This implies a perfect knowledge of the patient and its physiological changes, so close cooperation with the physician in charge of the patient. Finally, regulatory and economic conditions for using the products now define a framework of strict requirement that only a confrontation argued closely and medical and pharmaceutical may qualify.