Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10889835 | Journal of Microbiological Methods | 2010 | 4 Pages |
Abstract
Helicobacter pylori bacterial ghosts, HPBG, were generated by PhiX174 mechanism and loaded with recombinant Omp18, which were then applied in therapeutic immunization of Hp-infected C57BL/6 mice. Recombinant Omp18 loaded HPBG plus cholera toxin stimulated serum anti-Hp and Omp18-specific antibodies which resulted in significant reduction of gastric Hp colonization (PÂ <Â 0.05).
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Authors
Y. Talebkhan, M. Bababeik, M. Esmaeili, A. Oghalaei, S. Saberi, Z. Karimi, N. Afkhami, M. Mohammadi,