Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10890674 | Journal of Microbiological Methods | 2011 | 4 Pages |
Abstract
Rapid and reliable assessment of Acinetobacter baumannii resistance to quinolones was successfully achieved through pyrosequencing of the gyrA and parC quinolone-resistance determining regions. A strong correlation was found between quinolone resistance and mutations in gyrA codon 83 and/or in the parC gene (codons 80 or 84). Absence of QRDR mutations was associated with susceptibility to quinolones.
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Authors
Yann Deccache, Léonid M. Irenge, Encho Savov, Mihaela Ariciuc, Alexandra Macovei, Angelina Trifonova, Ivanka Gergova, Jérôme Ambroise, Raymond Vanhoof, Jean-Luc Gala,