| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10914895 | Molecular Oncology | 2013 | 11 Pages |
Abstract
⺠35.7% of CRC stage III tumors have TOP1 copy number. ⺠>4n. ⺠TOP1 copy number was associated with OS (HR: 0.62; p = 0.01).
Keywords
Antigen Ki-67mCRCTTRTop1DFS5FUKi67SN38TOP2Atopoisomerase 17-ethyl-10-hydroxy-camptothecinFFPEPFsstandard deviationDisease free survivalProgression free survivaloverall survivalBiomarkertime to recurrenceColorectal cancerRectal cancerColon cancerGene copy numberconfidence intervalformalin-fixed paraffin-embeddedfluorescence in situ hybridization5-fluorouracilFishhazard ratioREMARKprognosisCRC
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Authors
Maria Unni Rømer, Sune Boris NygÃ¥rd, Ib Jarle Christensen, Signe Lykke Nielsen, Kirsten Vang Nielsen, Sven Müller, David Hersi Smith, Ben Vainer, Hans Jørgen Nielsen, Nils Brünner,