| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10962075 | Tuberculosis | 2014 | 7 Pages |
Abstract
Thioridazine is bactericidal towards Mtb in vitro, irrespective the mycobacterial growth rate and results in enhanced activity of the standard regimen. The in vitro activity of thioridazine in potentiating isoniazid and rifampicin is not reflected by improved therapeutic efficacy in a murine TB-model.
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Authors
Gerjo J. de Knegt, Marian T. ten Kate, Dick van Soolingen, Rob Aarnoutse, Martin J. Boeree, Irma A.J.M. Bakker-Woudenberg, Jurriaan E.M. de Steenwinkel,