Article ID Journal Published Year Pages File Type
10962081 Tuberculosis 2013 8 Pages PDF
Abstract
Anti-mycobacterial immunity is guided by specialised antigen presenting cells known as dendritic cells, which are essential for both initiating and maintaining T cell immune responses during infection. The dendritic cell population can be divided into functionally distinct subsets that differ in their ability to present antigen and produce key TH1 cytokines, such as IL-12. This review discusses recent studies, in murine models, investigating which dendritic cell populations are important for mycobacterial control.
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Life Sciences Immunology and Microbiology Applied Microbiology and Biotechnology
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