Article ID Journal Published Year Pages File Type
10962083 Tuberculosis 2013 6 Pages PDF
Abstract
Even though several mechanisms are involved in regulating the human immune response, biological environment seems to be determinant. In this context, the integrated neuro-immune-endocrine system strongly influences TB clinical outcome. One of the most important clinical aspects of TB is shown when the infection locates in the central nervous system (CNS), in which a very different set of immune responses is induced. Herein we review several aspects of the paradoxical immune response triggered during CNS-TB infection, and discuss the implications of this response in the cerebral infection outcome.
Related Topics
Life Sciences Immunology and Microbiology Applied Microbiology and Biotechnology
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