Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10962083 | Tuberculosis | 2013 | 6 Pages |
Abstract
Even though several mechanisms are involved in regulating the human immune response, biological environment seems to be determinant. In this context, the integrated neuro-immune-endocrine system strongly influences TB clinical outcome. One of the most important clinical aspects of TB is shown when the infection locates in the central nervous system (CNS), in which a very different set of immune responses is induced. Herein we review several aspects of the paradoxical immune response triggered during CNS-TB infection, and discuss the implications of this response in the cerebral infection outcome.
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Authors
Brenda Sáenz, Rogelio Hernandez-Pando, Gladis Fragoso, Oscar Bottasso, Graciela Cárdenas,