Article ID Journal Published Year Pages File Type
11007575 The Journal of Nutritional Biochemistry 2018 30 Pages PDF
Abstract
Mechanism of GSPE ameliorating lead-induced heart injury. In rat heart, lead induced ER stress and inactivated AKT/GSK3β signaling contributing to oxidative stress and apoptosis. However, GSPE protects cardiocytes against lead via reducing lead accumulation, alleviating ER stress, activating AKT/GSK3β signaling, and furtherly attenuating oxidative stress and apoptosis.66
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Dietary grape seed procyanidin extract protects against lead-induced heart injury in rats involving endoplasmic reticulum stress inhibition and AKT activation
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