Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
11017052 | Gastroenterología y Hepatología | 2018 | 16 Pages |
Abstract
The management of inflammatory bowel disease (IBD) is currently based on the objective evaluation of intestinal lesions. It would therefore be interesting to have access to simple and non-invasive tools to monitor IBD activity and to identify the presence of lesions. Faecal calprotectin (FC) is the main cytosolic protein of neutrophils, it is resistant to bacterial degradation and it is stable at room temperature for several days, characteristics that make it suitable for use in clinical practice. It can be used to differentiate between inflammatory and functional processes, it correlates with endoscopic activity, it is associated with clinical and endoscopic response to treatment and it has short-term prognostic value. This paper offers an up-to-date perspective on the information that FC can provide clinicians to aid diagnosis, monitoring and management of IBD.
Keywords
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Gastroenterology
Authors
Jordi Guardiola, Triana Lobatón, Elena Cerrillo, RocÃo Ferreiro-Iglesias, Javier P. Gisbert, Eugeni Domènech, MarÃa Chaparro, Maria Esteve, Francisco RodrÃguez-Moranta, en representación de GETECCU en representación de GETECCU,