A preclinical evaluation of cytarabine prodrug nanofibers assembled from cytarabine-lauric acid conjugate toward solid tumors

Article ID	Journal	Published Year	Pages	File Type
11023109	International Journal of Pharmaceutics	2018	8 Pages	PDF

Keywords

IC50 HFS PLT MTD CREA PPE ALT RBC WBC ABCB Ara-U AML Nano-DDS Red blood cells 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide DMSO H&E MTT Ara-C Ara-CTP serum aspartate aminotransferase AST aminotransferase TIR Maximum tolerated dose BUN dimethyl sulphoxide normal saline Cancer therapy Toxicity cytarabine lauric acid Acute lymphoblastic leukaemia Acute myeloid leukaemia Nanofibers blood urea nitrogen half-maximal inhibitory concentration Hematoxylin and Eosin ALL Hemoglobin Blood platelet Pept1 creatine white blood cells

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A preclinical evaluation of cytarabine prodrug nanofibers assembled from cytarabine-lauric acid conjugate toward solid tumors

Authors

Ruiling Liu, Yue Jiang, Xu Hu, Jilian Wu, Wei Jiang, Guoxia Jin, Yuxia Luan,