| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 11025646 | Toxicology in Vitro | 2019 | 28 Pages |
Abstract
The results suggested that the potential of 3PHBO-12 and 3HHDMP-12 to induce skin irritation is comparable to or less than that of existing antiseptics, and these bis-QACs may be useful antiseptics with few side effects.
Keywords
CCK-8PBSPHMBRT-PCRWSTPolyhexamethylene biguanideBACMTTdistilled waterReconstructed human epidermisOctOctenidine dihydrochlorideBenzalkonium chlorideELISAEnzyme-linked immunosorbent assayCytotoxicity assayInflammatory cytokinescell counting kit-8AntisepticsPhosphate-buffered salinereverse-transcription polymerase chain reactionchgKeratinocytesChlorhexidine digluconate
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Authors
Masashi Yamamoto, Reiko Matsumura, Yoshihiko Hirata, Hideaki Nagamune,