The influence of compatibility of Si-Ni decoction with metabolism in intestinal bacteria on transports of toxic diterpenoid alkaloids from processed aconite root across Caco-2 monolayers

Article ID	Journal	Published Year	Pages	File Type
11025717	Journal of Ethnopharmacology	2019	43 Pages	PDF

Keywords

P-gp HRMS Q-TOF Mrp2 Bcrp TEER UPLC TIC TCM SGLT1 basolateral DDAs QqQ Davidigenin MDAS ESI SND 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide MTT P-glycoprotein [6]-Gingerol ALD Diterpenoid alkaloids Apical Retention time quadrupole time-of-flight Compatibility SIM apparent permeability coefficient traditional Chinese medicine Mass spectrometry transepithelial electrical resistance EIC efflux ratio selected-ion monitoring Papp multidrug resistance-associated protein 2 breast cancer resistance protein Triple quadrupole Ultra-performance liquid chromatography extracted ion chromatogram total ion chromatogram electrospray ionization

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology

The influence of compatibility of Si-Ni decoction with metabolism in intestinal bacteria on transports of toxic diterpenoid alkaloids from processed aconite root across Caco-2 monolayers

Authors

Min Zhang, Ying Peng, Mengyue Wang, Beibei Gao, Lijuan Zhao, Xiaobo Li,