Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
11029395 | The International Journal of Biochemistry & Cell Biology | 2018 | 27 Pages |
Abstract
TPT ameliorates the hypoxia-induced pulmonary vascular remodeling in PAH, and the mechanism is associated with TPT-mediated inhibition of hypoxia-induced upregulation of HIF-1α and TRPC1/4/6 expression, Ca2+ influx, and PASMCs proliferation.
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Authors
Yongliang Jiang, Yumin Zhou, Gongyong Peng, Nian Liu, Heshen Tian, Dan Pan, Lei Liu, Xing Yang, Chao Li, Wen Li, Ling Chen, Pixin Ran, Aiguo Dai,