Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1147540 | Journal of Statistical Planning and Inference | 2017 | 8 Pages |
Abstract
We consider response-adaptive design of clinical trials under a variance-penalized criterion in the presence of mismeasurement. An explicit expression for the variance-penalized criterion with misclassified dichotomous responses is derived for response-adaptive designs and some properties are discussed. A new target proportion of treatment allocation is proposed under the criterion and related simulation results are presented.
Related Topics
Physical Sciences and Engineering
Mathematics
Applied Mathematics
Authors
Xuan Li, Xikui Wang,