Article ID Journal Published Year Pages File Type
1147540 Journal of Statistical Planning and Inference 2017 8 Pages PDF
Abstract
We consider response-adaptive design of clinical trials under a variance-penalized criterion in the presence of mismeasurement. An explicit expression for the variance-penalized criterion with misclassified dichotomous responses is derived for response-adaptive designs and some properties are discussed. A new target proportion of treatment allocation is proposed under the criterion and related simulation results are presented.
Related Topics
Physical Sciences and Engineering Mathematics Applied Mathematics
Authors
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