Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1148893 | Journal of Statistical Planning and Inference | 2014 | 8 Pages |
Abstract
We consider cross-over designs for a model that includes specific carryover effects when a treatment is preceded by itself. When the parameters of interest are total effects, i.e. the sum of direct effects of treatment and self-carryover effects, we show that optimal designs are a compromise between designs balanced on subjects such as balanced binary block designs and designs with subjects having a single treatment. We also propose universally optimal designs with a reduced number of subjects.
Related Topics
Physical Sciences and Engineering
Mathematics
Applied Mathematics
Authors
Pierre Druilhet, Walter Tinsson,